Healing and Antisecretory Effects of Aqueous Extract of Eremomastax speciosa (Acanthaceae) on Unhealed Gastric Ulcers

Table 4

Effect of E. speciosa on histamine-induced gastric acid hypersecretion (after 0.5 hr) in rats subjected to “unhealed gastric ulcers.”

Treatment	Dose (mg/kg)		Volume of gastric; juice (ml)	Gastric pH	Gastric acidity; (mEq/l)	% reduction of gastric acidity
Control 1	—	5	2.30 ± 0.26	2.56 ± 0.20	88.30 ± 0.92
E. speciosa	200	5	3.74 ± 0.04	3.59 ± 0.15	59.00 ± 4.08	33.18
E. speciosa	400	5	4.51 ± 0.32	3.77 ± 0.20	46.44 ± 3.29	47.41

: number of rats. The values are expressed as mean ± SEM; ; ; statistically different compared to control.