Healing and Antisecretory Effects of Aqueous Extract of Eremomastax speciosa (Acanthaceae) on Unhealed Gastric Ulcers

Table 6

Effect of E. speciosa on histamine-induced gastric acid hypersecretion (after 12 hr) in rats subjected to “unhealed gastric ulcers.”

Treatment	Dose (mg/kg)		Volume of gastric juice (ml)	Gastric pH	Gastric acidity; (mEq/l)	% reduction of gastric acidity
Control	—	5	5.22 ± 0.26	3.42 ± 0.24	89.60 ± 3.24	—
E. speciosa	200	5	2.64 ± 0.11	4.04 ± 0.29	67.60 ± 5.49	24.55
E. speciosa	400	5	4.10 ± 0.13	4.88 ± 0.41	63.06 ± 5.25	29.62

= 5 rats per treatment. The values are expressed as mean ± SEM; ;; ; statistically different compared to control.