Healing and Antisecretory Effects of Aqueous Extract of Eremomastax speciosa (Acanthaceae) on Unhealed Gastric Ulcers

Table 7

Antioxidant effects of E. speciosa in rats subjected to “unhealed gastric ulcers”/pylorus ligature.

Treatment	Dose (mg/kg)	SOD; (U/mg protein)	Catalase; (µmol H2O2/min/mg protein)	GSH; (mmol/g protein)	Malondialdehyde; (pmol/mg protein)
Normal rats	—	7.54 ± 0.16	5.22 ± 0.22	2.61 ± 0.02	1.60 ± 0.07
Control 1	—	4.02 ± 1.53	0.54 ± 0.03	0.85 ± 0.80	4.04 ± 0.25
Control 2	—	4.50 ± 0.37	0.65 ± 0.04	0.96 ± 0.11	4.46 ± 0.37
E. speciosa	200	6.82 ± 0.28	5.83 ± 0.23	3.24 ± 0.24	2.25 ± 0.01
E. speciosa	400	7.79 ± 0.08	7.84 ± 0.28	4.89 ± 0.18	1.50 ± 0.06
Sucralfate	50	7.25 ± 0.32	5.04 ± 0.20	2.37 ± 0.10	2.58 ± 0.34

= 5 rats per treatment. Control 1: ulcerated rats sacrificed 5 days after ulcer induction. The values are expressed as mean ± SEM; < 0.05; < 0.01; < 0.001; statistically different compared to normal rats; < 0.01; < 0.001; statistically different compared to Control 2.