Research Article

Antiurolithiasis Activity of Bioactivity Guided Fraction of Bergenia ligulata against Ethylene Glycol Induced Renal Calculi in Rat

Table 3

Effect of mother extract and DCM fraction of B. ligulata on various urolithiasis factors in serum parameters of ethylene glycol induced urolithiasis in Wistar rats.

GroupSerum parameter (mg/dL)
CalciumOxalatePhosphateUric acidUreaCreatinineAlbuminTotal protein

Normal control6.5 ± 0.141.2 ± 0.084.3 ± 0.132.4 ± 0.0838 ± 1.140.7 ± 0.124.2 ± 0.218.2 ± 0.08
Urolithiatic control
Mother extract4.5 ± 0.24###1.4 ± 0.12###3.8 ± 0.13###
DCM fraction3.9 ± 0.15###1.8 ± 0.13##4.0 ± 0.18##7.3 ± 0.09#
Neeri2.7 ± 0.06###1.6 ± 0.14###32 ± 0.87##4.1 ± 0.17##
Sham (ME)

All values are expressed as mean ± SEM of 6 rats (); , , , and  ; denotes that data were compared with normal control and # denotes that data were with urolithiatic control . .