The Combination of the Tumor Markers Suggests the Histological Diagnosis of Lung Cancer

Table 3

The criteria of lung cancer histological diagnosis.

	Criteria	Correct classification/total
NSCLC	SCC ≥ 2 ng/mL and ProGRP < 100 pg/mL [1]; SCC < 2 ng/mL and ProGRP < 100 pg/mL and CYFRA21-1 > 3.3 ng/mL [2]; SCC < 2 ng/mL and ProGRP < 100 pg/mL and CEA > 5 ng/mL [3]	233/238 (97.89%); 492/530 (92.83%); 403/423 (95.27%)
SCLC	SCC < 2 ng/mL and ProGRP ≥ 100 pg/mL and NSE ≥ 35 ng/mL [4]; SCC < 2 ng/mL and ProGRP > 150 pg/mL [5]	32/35 (91.42%); 57/63 (90.48%)
Adenocarcinoma	SCC < 2 ng/mL and ProGRP < 100 pg/mL and CEA > 5 ng/mL [3]	363/423 (85.81%)
Squamous carcinoma	[1] and CA125 < 100 U/mL and CYFRA21-1 ≥ 3.3 ng/mL [6]	120/151 (79.47%)