Research Article
The Combination of the Tumor Markers Suggests the Histological Diagnosis of Lung Cancer
Table 3
The criteria of lung cancer histological diagnosis.
| | Criteria | Correct classification/total |
| NSCLC | SCC ≥ 2 ng/mL and ProGRP < 100 pg/mL [1] SCC < 2 ng/mL and ProGRP < 100 pg/mL and CYFRA21-1 > 3.3 ng/mL [2] SCC < 2 ng/mL and ProGRP < 100 pg/mL and CEA > 5 ng/mL [3] | 233/238 (97.89%) 492/530 (92.83%) 403/423 (95.27%) |
| SCLC | SCC < 2 ng/mL and ProGRP ≥ 100 pg/mL and NSE ≥ 35 ng/mL [4] SCC < 2 ng/mL and ProGRP > 150 pg/mL [5] | 32/35 (91.42%) 57/63 (90.48%) |
| Adenocarcinoma | SCC < 2 ng/mL and ProGRP < 100 pg/mL and CEA > 5 ng/mL [3] | 363/423 (85.81%) |
| Squamous carcinoma | [1] and CA125 < 100 U/mL and CYFRA21-1 ≥ 3.3 ng/mL [6] | 120/151 (79.47%) |
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