Cytotoxic Effect on Human Myeloma Cells and Leukemic Cells by the Agaricus blazei Murill Based Mushroom Extract, Andosan™

Table 1

Cytotoxic effect of Andosan on myeloma cells from 8 patients. The numbers of viable cells after 72 hrs of culture were noted and converted to per cent of controls (100%). Mean: mean of duplicates; SE: standard error. Comparison of means of controls versus means of cultures with Andosan 4% showed a statistically significant difference ().

Patient number	Control	Andosan 0.5%	Andosan 1.0%	Andosan 2.0%	Andosan 4.0%
139
Mean	100	93.69	99.12	97.61	80.47
SE	4.04	1.35	1.11	2.11	0.44
244
Mean	100	117.91	122.5	114.15	110.22
SE	1.33	2.07	2.1	4.19	2.13
969
Mean	100	65.73	62.3	55.42	52.37
SE	1.95	2.18	2.22	2.66	2.39
185
Mean	100	86.6	83.14	73.71	52.28
SE	0.88	1.38	0.66	1.82	0.77
409
Mean	100	69.24	55.75	50.6	17.66
SE	1.5	2.05	2.05	2.05	2.18
715
Mean	100	90.35	86.8	84.12	73.11
SE	1.54	1.73	2.72	0.92	1.21
2925
Mean	100	91.81	90.92	80.78	54.27
SE	0.87	3.4	2.19	1.88	1.88
355
Mean	100	82.22	85.21	78.34	70.77
SE	2.17	2.64	2.39	3.15	2.95