Research Article

Cytotoxicity and Antimicrobial Effects of a New Fast-Set MTA

Table 1

Cytotoxicity evaluation of FS-MTA and RS-MTA, using evaluation criteria for agar diffusion test (ISO 7405, 2008). For zone index, 0 indicates no detectable decolorization zone; a score of 5 indicates a zone involving the entire dish. For lysis index, a score of 0 indicates no observable cytotoxicity, 5 indicates > 80% of the decolorized zone affected. For interpretation of cytotoxicity, score of 0 indicates being noncytotoxic, and 3 indicates severe toxicity.

Material24 hours48 hours
Zone indexLysis indexInterpretationZone indexLysis indexInterpretation

MEM (−control)00Noncytotoxic00Noncytotoxic
Cottonseed oil (−control)00Noncytotoxic00Noncytotoxic
Phenol (+control)55Severely cytotoxic55Severely cytotoxic
RS-MTA solid00Noncytotoxic00Noncytotoxic
RS-MTA MEM00Noncytotoxic00Noncytotoxic
RS-MTA oil00Noncytotoxic00Noncytotoxic
FS-MTA solid00Noncytotoxic00Noncytotoxic
FS-MTA MEM00Noncytotoxic00Noncytotoxic
FS-MTA oil00Noncytotoxic00Noncytotoxic