BioMed Research International / 2017 / Article / Tab 1

Research Article

Prognostic Significance of Preoperative and Postoperative Complement C3 Depletion in Gastric Cancer: A Three-Year Survival Investigation

Table 1

The demographic and baseline characteristics of patients with gastric cancer.

The pooledCD groupControl group value

Age, yrs56.4 ± 12.254.5 ± 15.157.2 ± 10.90.370
 ≤6582 (77.4)20 (66.7)62 (81.6)0.084
 >6524 (22.6)10 (33.3)14 (18.4)
Gender, male : female65 : 4116 : 1449 : 270.376
BMI, kg/m221.6 ± 3.320.9 ± 2.821.8 ± 3.40.231
Comorbidity, (%)
 HTN9 (8.5)3 (10.0)6 (7.9)0.710
 DM4 (3.8)2 (6.7)2 (2.6)0.317
Smoke, (%)26 (24.5)9 (30.0)17 (22.4)0.456
Alcohol abuse, (%)13 (12.3)11 (14.5)2 (6.7)0.342
ASA, (%)0.594
 I + II85 (80.2)23 (76.7)62 (81.6)
 ≥III21 (19.8)7 (23.3)14 (18.4)
Albumin level, g/dL38.1 ± 7.537.9 ± 4.638.2 ± 8.40.880
Operative time, min278.7 ± 78.4281.8 ± 71.8277.4 ± 81.40.796
Type of anastomosis, (%)0.661
 Billroth I2 (1.9)02 (2.6)
 Billroth II11 (10.4)3 (10.0)8 (10.5)
 Roux-en-Y51 (48.1)15 (50.0)36 (47.4)
Gastrectomy technique, (%)0.803
 Proximal gastrectomy13 (12.3)3 (10.0)10 (13.2)
 Distal gastrectomy45 (42.4)12 (40.0)33 (43.4)
 Total gastrectomy48 (45.3)15 (50.0)33 (43.4)
Lymphadenectomy, (%)0.566
8 (7.5)1 (3.3)7 (9.2)
76 (71.7)23 (76.7)53 (69.7)
22 (20.8)6 (20.0)16 (21.1)
Depth of invasion, (%)0.251
 pT18 (7.6)1 (3.3)7 (9.2)
 pT211 (10.3)1 (3.3)10 (13.1)
 pT39 (8.5)2 (6.7)7 (9.2)
 pT478 (73.6)26 (86.7)52 (68.4)
Lymph nodes retrievals, 39.2 ± 18.841.9 ± 18.438.1 ± 19.0
Lymph nodes metastases, (%)0.650
 pN031 (29.2)11 (36.7)21 (27.6)
 pN114 (13.2)3 (10.0)11 (14.5)
 pN219 (17.9)4 (13.3)16 (21.1)
 pN340 (37.7)12 (40.0)28 (36.8)
Histopathological type, (%)0.978
 Well diff.7 (6.6)2 (6.7)5 (6.5)
 Moderate diff.19 (17.9)5 (16.7)14 (18.4)
 Poor diff.80 (75.5)23 (76.6)57 (75.0)
pTNM Stage, (%)0.223
 I12 (11.3)1 (3.3)11 (14.5)
 II25 (23.6)10 (33.3)15 (19.7)
 III55 (51.9)16 (53.4)39 (51.3)
 IV14 (13.2)3 (10.0)11 (14.5)

Patients were divided into CD group and control group based on baseline levels of C3 (cutoff value, 0.75 mg/mL). Data present with mean ± SD or number (percentage of column). CD, complement depletion; BMI, body mass index; HTN, hypertension; DM, diabetes mellitus; ASA, American Society of Anesthesia; diff., differentiation. plus means extended lymphadenectomy beyond stations during gastrectomy.

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