Systems Study on the Antirheumatic Mechanism of Tibetan Medicated-Bath Therapy Using Wuwei-Ganlu-Yaoyu-Keli

Table 1

Selection of the most significantly enriched and specific GO terms in the network modules.

Module	GO term (biological process)	Level	Total genes	Mapped genes
()	Positive regulation of interleukin-5 secretion	9	14	13
	Positive regulation of interleukin-13 secretion	9	14	13
	Positive regulation of T-helper 2 cell cytokine production	11	15	13
	Positive regulation of interleukin-10 secretion	9	15	13
()	JAK-STAT cascade	5	57	12
	JAK-STAT cascade involved in growth hormone signaling pathway	9	26	8
	Cytokine-mediated signaling pathway	6	406	15
()	Positive regulation of neuron differentiation	7	342	6
	Positive regulation of neurogenesis	7	472	6
	Positive regulation of neuron projection development	8	208	5
()	Positive regulation of leukocyte differentiation	6	137	19
	Positive regulation of hemopoiesis	6	166	19
	Regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	3	127	16
()	MyD88-dependent toll-like receptor signaling pathway	8	92	11
	Innate immune response-activating signal transduction	8	157	11
()	Immune response-activating cell surface receptor signaling pathway	7	350	33
	Antigen receptor-mediated signaling pathway	7	158	27
()	Positive regulation of MAPK cascade	10	512	39
()	Regulation of interleukin-12 biosynthetic process	6	16	9
	Positive regulation of type I interferon production	5	57	11
	Activation of innate immune response	7	170	13
	Positive regulation of cytokine biosynthetic process	10	87	11
	Regulation of I-kappaB kinase/NF-kappaB signaling	4	249	14
()	Cellular response to insulin stimulus	8	255	30
	Peripheral nervous system myelin maintenance	9	29	17
()	Apoptotic signaling pathway	5	310	18
()	Positive regulation of cell proliferation	3	964	16
()	Transmembrane receptor protein serine/threonine kinase signaling pathway	5	273	20
	Cellular response to growth factor stimulus	4	719	19