BioMed Research International / 2017 / Article / Tab 1

Research Article

Systems Study on the Antirheumatic Mechanism of Tibetan Medicated-Bath Therapy Using Wuwei-Ganlu-Yaoyu-Keli

Table 1

Selection of the most significantly enriched and specific GO terms in the network modules.

Module GO term (biological process)Level Total genes Mapped genes

()Positive regulation of interleukin-5 secretion91413
Positive regulation of interleukin-13 secretion91413
Positive regulation of T-helper 2 cell cytokine production111513
Positive regulation of interleukin-10 secretion91513

()JAK-STAT cascade55712
JAK-STAT cascade involved in growth hormone signaling pathway9268
Cytokine-mediated signaling pathway640615

()Positive regulation of neuron differentiation73426
Positive regulation of neurogenesis74726
Positive regulation of neuron projection development82085

()Positive regulation of leukocyte differentiation613719
Positive regulation of hemopoiesis616619
Regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains312716

()MyD88-dependent toll-like receptor signaling pathway89211
Innate immune response-activating signal transduction815711

()Immune response-activating cell surface receptor signaling pathway735033
Antigen receptor-mediated signaling pathway715827

()Positive regulation of MAPK cascade1051239

()Regulation of interleukin-12 biosynthetic process6169
Positive regulation of type I interferon production55711
Activation of innate immune response717013
Positive regulation of cytokine biosynthetic process108711
Regulation of I-kappaB kinase/NF-kappaB signaling424914

()Cellular response to insulin stimulus825530
Peripheral nervous system myelin maintenance92917

()Apoptotic signaling pathway531018

()Positive regulation of cell proliferation396416

()Transmembrane receptor protein serine/threonine kinase signaling pathway527320
Cellular response to growth factor stimulus471919

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