Research Article
Systems Study on the Antirheumatic Mechanism of Tibetan Medicated-Bath Therapy Using Wuwei-Ganlu-Yaoyu-Keli
Table 2
Genes encoding drug targets for FDA approved anti-RA drugs that appear in the network modules.
| Module | Drug target | Drug | Drug class |
| () | JAK1 | Tofacitinib | DMARDs | JAK2 | Tofacitinib | DMARDs |
| () | IL1B | Canakinumab | Biotech agents | IL6R | Tocilizumab | Biotech agents | LTA | Etanercept | Biotech agents | TNF | Etanercept | Biotech agents | Adalimumab | Biotech agents | Infliximab | Biotech agents | Golimumab | Biotech agents | Certolizumab pegol | Biotech agents | Chloroquine | DMARDs | TNFRSF1B | Etanercept | Biotech agents |
| () | IL1R1 | Anakinra | Biotech agents |
| () | PTK2B | Leflunomide | DMARDs |
| () | MAPK3 | Sulindac | NSAIAs |
| () | CHUK | Sulfasalazine | DMARDs | IKBKB | Sulfasalazine | DMARDs | Auranofin | DMARDs |
| () | PDPK1 | Celecoxib | NSAIAs |
| () | BCL2 | Ibuprofen | NSAIAs |
|
|