IFN-τ Displays Anti-Inflammatory Effects on Staphylococcus aureus Endometritis via Inhibiting the Activation of the NF-κB and MAPK Pathways in Mice

Figure 3

Effects of IFN-τ on MPO activity in uterus tissues (HE, ×200). Immunohistochemical illustrates MPO activity in sections of uterine tissues. (a) Control group (CG), the mice were without any treatment. (b) S. aureus-infected group (S. aureus), the mice were infected with S. aureus. (c) Dexamethasone group (DEX), the mice of S. aureus endometritis were treatment with DEX. (d)–(f) IFN-τ groups, the mice of S. aureus endometritis were treatment with different concentrations of IFN-τ (2, 4, 8 mg/kg). (g) Effects of different doses of IFN-τ (2, 4, 8 mg/kg) and dexamethasone (5 mg/kg) on myeloperoxidase activity in mice with S. aureus-infected uterine tissues. Data are expressed as the means ± SD (). , significantly different from the CG; ^#, significantly different from the S. aureus group.