Altered Erythropoiesis in Mouse Models of Type 3 Hemochromatosis
(a) Comparison between 14-day (14 d) and 10-week (10 w) Tfr2β expression (on the left) and production (on the right) in splenic macrophages of wild type (WT) animals. (b) Quantification of divalent metal transporter 1 (DMT1), Ferroportin 1 (Fpn1) and ferritin L (Ft-L) protein production resulting from Western blot analysis of splenic macrophages isolated from WT, KI, and KO mice at 14 d and 10 w of ages. a.u.: arbitrary unit; SPL: total spleen. indicates statistically significant difference ().
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