Prediction and Validation of Hub Genes Associated with Colorectal Cancer by Integrating PPI Network and Gene Expression Data

Figure 4

Pathway enrichment analysis of DEGs. (a) Enrichment plots for significant pathways identified by GSEA include Wnt signaling pathway, cell cycle, Hippo signaling pathway, spliceosome, RNA transport, ribosome, calcium signaling pathway, cell adhesion molecules (CAMs), cGMP-PKG signaling pathway, and cAMP signaling pathway. (b-c) The signaling pathway of Wnt and cell cycle (this image was obtained by Kyoto Encyclopedia of Genes and Genomes with permission). Red represents the upregulated genes, while green represents the downregulated genes.

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