Comparative Study of Elastic Network Model and Protein Contact Network for Protein Complexes: The Hemoglobin Case

Figure 2

ENM results for transition of tetrameric Hb. (a) Overlaps between the ten slowest ANM modes of - and -Hbs. (b) Distribution of mean-square fluctuations obtained by the first ANM mode of - and -Hbs. The residue index of the four chains is 1–140 (), 141–285 (), 286–425 (), and 426–570 (). (c) Overlaps of individual -Hb ANM modes with the conformational change within transition. (d) The motion of the second ANM mode of -Hb; here the protein is represented as a network.

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