Research Article
Mutagenic and Cytotoxicity LQB 123 Profile: Safety and Tripanocidal Effect of a Phenyl-t-Butylnitrone Derivative
Table 1
LQB 123 effect upon Trypanosoma cruzi forms.
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The trypanocidal activity was expressed as the IC50, corresponding to the concentration that leads to 50% parasite lysis. CC50 > 4000 μM (drug concentration which reduced 50% of peritoneal macrophage viability). SI (selectivity index) = CC50/IC50. |