Predictors of Extracorporeal Membrane Oxygenation Support for Children with Acute Myocarditis

Table 3

Comparison of the laboratory tests of patients with acute myocarditis based on management with ECMO or not.

Variables	No ECMO support			ECMO support			P value
		Mean	SD		Mean	SD
WBC (×10^9/L)	50	11481.80	4610.77	10	9210.00	3117.85	0.148
CRP (mg/L)	35	2.62	3.60	10	6.26	11.42	0.246
Troponin-I (ng/mL)	50	4.88	10.01	10	25.48	30.95	0.026
CK (U/L)	34	812.87	1934.62	7	1327.14	1440.69	0.212
CK-MB (ng/mL)	38	32.68	55.16	10	122.73	163.03	0.041
Sodium (mmol/L)	43	137.84	3.93	10	139.20	10.65	0.599
Potassium (mmol/L)	43	3.86	0.69	10	4.32	1.78	0.480
Calcium (mg/dL)	24	8.98	0.78	9	7.17	1.42	0.001
AST (U/L)	18	163.78	472.55	10	291.30	208.67	0.001
ALT (U/L)	27	79.70	269.90	10	117.60	101.94	0.001
BUN (mg/dL)	20	13.90	15.99	10	25.80	14.57	0.001
Creatinine (mg/dL)	33	0.62	0.33	10	1.50	0.97	<0.001
LVEF (%)	49	66.90	9.04	10	46.10	18.61	<0.001
Lactate (mmol/L)	6	3.83	4.58	5	10.02	5.42	0.242
NT-proBNP (pg/mL)	8	5938.88	11977.87	5	8560.60	9730.98	0.030

Statistically significant according to the Mann–Whitney test.
ECMO = extracorporeal membrane oxygenation; WBC = white blood count; CRP = C-reactive protein; CK = creatine phosphokinase; CK-MB = creatine phosphokinase-MB; AST = aspartate aminotransferase; ALT = alanine aminotransferase; BUN = blood urea nitrogen; LVEF = left ventricular ejection fraction; NT-proBNP = N-terminal prohormone of brain natriuretic peptide.