Silencing CAPN2 Expression Inhibited Castration-Resistant Prostate Cancer Cells Proliferation and Invasion via AKT/mTOR Signal Pathway

Figure 2

Knockdown of CAPN2 inhibits proliferation in DU145 and PC3 cell lines. (a) CRPC cell proliferation was measured by CCK-8 assay. The results showed that the proliferation of DU145 and PC3 cells was significantly inhibited after being transfected with si-CPAN2. (b) Analysis of cell cycle in CRPC cells indicated that the treated cells were arrested at G1. Data are presented as mean ± SEM. by -test.

(a)

(b)