Silencing CAPN2 Expression Inhibited Castration-Resistant Prostate Cancer Cells Proliferation and Invasion via AKT/mTOR Signal Pathway

Figure 3

(a) Effect of CAPN2 on wound healing of PC3 and DU145 cells. The invasion of cells in which CAPN2 was downregulated was analyzed by a wound healing assay. (b, c) The decreased CAPN2 expression suppressed the invasion of DU145 and PC3. The invasion of the treated cells was evaluated in an invasion assay using a transwell insert coated with Matrigel. Data are presented as mean ± SEM. compared with Blank or NC.

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