Regulation of Matrix Metalloproteinase-2 Secretion from Scleral Fibroblasts and Retinal Pigment Epithelial Cells by miR-29a

Figure 2

The effects of miR-29a on the viability and growth of scleral fibroblasts and retinal pigment epithelial (RPE) cells. Scleral fibroblasts and RPE cells were seeded at a final density of 3 × 10³/well and cultured in 96-well plates. The cells in each well were transfected with 50 nM miR-29a mimics or 50 nM inhibitor. The miR-29a mimics or inhibitor had no significant effect on the growth of scleral fibroblasts (a) or RPE cells (b) at 24, 48, or 72 hours after transfection compared with the negative controls (). Note: the error bars show the standard deviations (). The statistical analyses were performed using one-way ANOVA. NC, negative control.

(a)

(b)