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BioMed Research International
Volume 2017, Article ID 2674726, 7 pages
Research Article

Relation of ABO Blood Groups to the Plaque Characteristic of Coronary Atherosclerosis

Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, Heilongjiang, China

Correspondence should be addressed to Jingbo Hou; moc.361@uohobgnij

Received 28 August 2017; Revised 1 October 2017; Accepted 10 October 2017; Published 8 November 2017

Academic Editor: Gianluca Pontone

Copyright © 2017 Xingtao Huang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The ABO blood types related to morphological characteristics of atherosclerosis plaque are not clear. We aimed to evaluate the relationship between ABO blood groups and the coronary plaque characteristic. We retrospectively identified the target lesions in 392 acute coronary syndrome patients who underwent optical coherence tomography examination before stenting. Subjects were divided into different groups according to different blood types. The fibrous cap thickness was significantly thicker in O type compared with non-O type ( mm versus , ). Meanwhile, the incidence of thin-cap fibroatheroma was also significantly higher in O type compared with non-O type (51.0% versus 71.5%, ). The O type showed a significantly larger minimum lumen area 1.26 (0.82, 2.13) versus 1.05 (0.67, 1.82), and minimum lumen diameter 1.03 (0.74, 1.31) versus 0.95 (0.66, 1.25), compared with non-O type. There were no differences found in incidence of lipid plaque, plaque rupture, and thrombus between different blood type groups even between O type and non-O type group (). The plaques of O type blood group were exhibited more stably compared with non-O type blood group. Moreover, the non-O type blood group have more serious coronary artery stenosis than O type blood group.