Table 2: Monocyte subpopulation frequency and osteoclastogenic marker expression.

BaselineFollow-up value

Classic (%)88 [82–89]78 [70–83]
Classic CD51/CD61 MFI130 [119–148]125 [111–137]0.4258
Classic RANK MFI133 [116–160]122 [100–135]0.1849

Intermediate 4.4 [2.4–5.6]4.0 [2.1–7.1]0.6013
Intermediate CD51/CD61 MFI222 [139–400]193 [146–240]0.8203
Intermediate RANK MFI197 [117–361]188 [120–272]0.9102

Nonclassic 5.7 [4.1–11]14 [11.5–18.1]
Nonclassic CD51/CD61 MFI192 [80–290]142 [127–167]0.5703
Nonclassic RANK MFI139 [122–157]138 [126–146]1.0000

Flow cytometry results are shown as median and interquartile range; on the monocyte subpopulation from peripheral blood mononuclear cells. RANK: receptor activator of nuclear factor-κB; MFI: median fluorescence intensity (arbitrary units); , . Remained significant after correction for multiple comparisons.