Review Article

Scientific Evidence for Different Options for GDM Screening and Management: Controversies and Review of the Literature

Table 3

RCTs comparing the One-Step to the Two-Step methods.

Author (origin)Study groupControl group (1)Control group (2)GDM ratePrimary outcome

Meltzer et al., 2010 (Canada) [19]One-Step (2 h, 75 g)Two-Step (50 g, 1 h; 100 g, 3 h)Two-Step (50 g, 1 h; 75 g, 3 h)3.6% versus 3.7% versus 3.7%Costs of screening
Sevket et al., 2013 (Turkey) [20]One-Step (2 h, 75 g)Two-Step (50 g, 1 h; 100 g, 3 h)14.5% versus 6%Maternal and neonatal outcomes
Scifres et al., 2014 (USA) [21]One-Step (2 h, 75 g)Two-Step (50 g, 1 h; 100 g, 3 h)4.3% versus 0.0%Maternal and neonatal outcomes