The lncRNA H19 Promotes Cell Proliferation by Competitively Binding to miR-200a and Derepressing β-Catenin Expression in Colorectal Cancer

Figure 3

β-Catenin is a target of miR-200a, and miR-200a represses β-catenin expression in HCT116 cells. (a) miR-200a reduces the luciferase activity of a WT β-catenin reporter plasmid, as demonstrated via a luciferase reporter assay (). (b) miR-200a overexpression decreases β-catenin levels, as demonstrated via western blot analysis. “” refers to .

(a)

(b)