Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2017, Article ID 2979307, 5 pages
https://doi.org/10.1155/2017/2979307
Research Article

The Diagnostic Roles of Cytokines in Hepatobiliary Cancers

1Department of General Surgery, School of Medicine, Suleyman Demirel University, Isparta, Turkey
2HPB Surgery Unit, Department of General Surgery, School of Medicine, Suleyman Demirel University, Isparta, Turkey

Correspondence should be addressed to Yavuz Savas Koca; moc.liamg@acoksavaszuvay

Received 15 June 2017; Revised 17 November 2017; Accepted 5 December 2017; Published 19 December 2017

Academic Editor: Jeroen T. Buijs

Copyright © 2017 Yavuz Savas Koca et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. K. Burak, P. Angulo, T. M. Pasha, K. Egan, J. Petz, and K. D. Lindor, “Incidence and Risk Factors for Cholangiocarcinoma in Primary Sclerosing Cholangitis,” American Journal of Gastroenterology, vol. 99, no. 3, pp. 523–526, 2004. View at Publisher · View at Google Scholar · View at Scopus
  2. G. Abbas and K. D. Lindor, “Cholangiocarcinoma in primary sclerosing cholangitis,” Journal of Gastrointestinal Cancer, vol. 40, no. 1-2, pp. 19–25, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. R. Roshani, F. McCarthy, and T. Hagemann, “Inflammatory cytokines in human pancreatic cancer,” Cancer Letters, vol. 345, no. 2, pp. 157–163, 2014. View at Publisher · View at Google Scholar · View at Scopus
  4. C. L. Slingluff Jr., “Immunology of cancer,” in Surgery; Basic Science and Clinical Evidence, J. A. Norton, Ed., Springer, New York, NY, USA, 2001. View at Google Scholar
  5. N. Cools, P. Ponsaerts, V. F. I. Van Tendeloo, and Z. N. Berneman, “Regulatory T cells and human disease,” Clinical and Developmental Immunology, vol. 2007, Article ID 89195, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. A. M. Wolf, D. Wolf, M. Steurer, G. Gastl, E. Gunsilius, and B. Grubeck-Loebenstein, “Increase of regulatory T cells in the peripheral blood of cancer patients,” Clinical Cancer Research, vol. 9, no. 2, pp. 606–612, 2003. View at Google Scholar · View at Scopus
  7. I. Barut and S. Kaya, “The diagnostic value of C-reactive protein in bacterial translocation in experimental biliary obstruction,” Advances in Clinical and Experimental Medicine, vol. 23, no. 2, pp. 197–203, 2014. View at Publisher · View at Google Scholar · View at Scopus
  8. U. K. Liyanage, T. T. Moore, H.-G. Joo et al., “Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma,” The Journal of Immunology, vol. 169, no. 5, pp. 2756–2761, 2002. View at Publisher · View at Google Scholar · View at Scopus
  9. L. Ormandy, T. Hillemann, H. Wedemeyer, M. P. Manns, T. F. Greten, and F. Korangy, “Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma,” Cancer Research, vol. 65, no. 6, pp. 2457–2464, 2005. View at Publisher · View at Google Scholar · View at Scopus
  10. C. Grande, J. L. Firvida, V. Navas, and J. Casal, “Interleukin-2 for the treatment of solid tumors other than melanoma and renal cell carcinoma,” Anti-Cancer Drugs, vol. 17, no. 1, pp. 1–12, 2006. View at Publisher · View at Google Scholar · View at Scopus
  11. S. Dempe, M. Lavie, S. Struyf et al., “Antitumoral activity of parvovirus-mediated IL-2 and MCP-3/CCL7 delivery into human pancreatic cancer: Implication of leucocyte recruitment,” Cancer Immunology, Immunotherapy, vol. 61, no. 11, pp. 2113–2123, 2012. View at Publisher · View at Google Scholar · View at Scopus
  12. Z. Xiao, G. Luo, C. Liu et al., “Molecular mechanism underlying lymphatic metastasis in pancreatic cancer,” BioMed Research International, vol. 2014, Article ID 925845, 2014. View at Publisher · View at Google Scholar · View at Scopus
  13. K. Heikkilä, S. Ebrahim, and D. A. Lawlor, “Systematic review of the association between circulating interleukin-6 (IL-6) and cancer,” European Journal of Cancer, vol. 44, no. 7, pp. 937–945, 2008. View at Publisher · View at Google Scholar · View at Scopus
  14. D. R. Hodge, E. M. Hurt, and W. L. Farrar, “The role of IL-6 and STAT3 in inflammation and cancer,” European Journal of Cancer, vol. 41, no. 16, pp. 2502–2512, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. M. Song and J. A. Kellum, “Interleukin-6,” Critical Care Medicine, vol. 33, no. 12, pp. S463–S465, 2005. View at Publisher · View at Google Scholar · View at Scopus
  16. B. B. Aggarwal, S. Shishodia, S. K. Sandur, M. K. Pandey, and G. Sethi, “Inflammation and cancer: how hot is the link?” Biochemical Pharmacology, vol. 72, no. 11, pp. 1605–1621, 2006. View at Publisher · View at Google Scholar · View at Scopus
  17. R. Holmer, F. A. Goumas, G. H. Waetzig, S. Rose-John, and H. Kalthoff, “Interleukin-6: A villain in the drama of pancreatic cancer development and progression,” Hepatobiliary & Pancreatic Diseases International, vol. 13, no. 4, pp. 371–380, 2014. View at Publisher · View at Google Scholar · View at Scopus
  18. J. L. Mott and G. J. Gores, “Targeting IL-6 in cholangiocarcinoma therapy,” American Journal of Gastroenterology, vol. 102, no. 10, pp. 2171-2172, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. D. Delitto, B. S. Black, H. L. Sorenson et al., “The inflammatory milieu within the pancreatic cancer microenvironment correlates with clinicopathologic parameters, chemoresistance and survival,” BMC Cancer, vol. 15, no. 1, article 783, 2015. View at Publisher · View at Google Scholar · View at Scopus
  20. Y. Matsuo, H. Sawai, H. Funahashi et al., “Enhanced Angiogenesis Due to Inflammatory Cytokines from Pancreatic Cancer Cell Lines and Relation to Metastatic Potential,” Pancreas, vol. 28, no. 3, pp. 344–352, 2004. View at Publisher · View at Google Scholar · View at Scopus
  21. C.-Y. Hsia, T.-I. Huo, S.-Y. Chiang et al., “Evaluation of interleukin-6, interleukin-10 and human hepatocyte growth factor as tumor markers for hepatocellular carcinoma,” European Journal of Surgical Oncology, vol. 33, no. 2, pp. 208–212, 2007. View at Publisher · View at Google Scholar · View at Scopus
  22. S. Karakhanova, E. Ryschich, B. Mosl et al., “Prognostic and predictive value of immunological parameters for chemoradioimmunotherapy in patients with pancreatic adenocarcinoma,” British Journal of Cancer, vol. 112, no. 6, pp. 1027–1036, 2015. View at Publisher · View at Google Scholar · View at Scopus
  23. J.-H. Egberts, V. Cloosters, A. Noack et al., “Anti-tumor necrosis factor therapy inhibits pancreatic tumor growth and metastasis,” Cancer Research, vol. 68, no. 5, pp. 1443–1450, 2008. View at Publisher · View at Google Scholar · View at Scopus
  24. P. Utaisincharoen, N. Tangthawornchaikul, S. Ubol, P. Chaisuriya, and S. Sirisinha, “Tnf-α induces caspase 3 (CPP 32) dependent apoptosis in human cholangiocarcinoma cell line,” Southeast Asian Journal of Tropical Medicine and Public Health, vol. 31, no. 1, pp. 167–170, 2000. View at Google Scholar · View at Scopus