Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) for the Treatment of Nonunion of the Femur in Children and Adolescents: A Retrospective Analysis

Figure 1

((a) and (b)) Anteroposterior preoperative (a) and postoperative (b) radiographs of a 10-year-old boy with infantile cerebral palsy with coxa antetorta who underwent femoral derotation osteotomy with use of a locking plate on both sides. (c) Anteroposterior radiograph of the same patient demonstrates persistent femoral nonunion with screw breakage of two femoral neck screws on the right side. (d) Anteroposterior radiograph two days after surgical revision with removal of the locking plate, resection of the femoral nonunion, application of rhBMP-2, and insertion of a new locking plate. (e) Anteroposterior radiograph 7.9 months after surgical intervention with use of rhBMP-2 demonstrating complete radiological healing which was still evident at the most recent follow-up, 60 months after rhBMP-2, was applied.

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