Clinical Significance of Preoperative Albumin and Globulin Ratio in Patients with Gastric Cancer Undergoing Treatment

Table 3

Prognostic value of AGR for overall survival in the validation group of GC patients by univariate and multivariate analyses.

Characteristics	Univariate analysis			Multivariate analysis
	Hazard ratio	95% CI	p value	Hazard ratio	95% CI	p value
Sex
Male versus female	1.121	0.81–1.552	0.49
Age (yr)
≤59 versus >59	1.015	1.002–1.029	0.021	1.080	0.705–1.653	0.723
Primary tumor size (cm)
<4.0 versus ≥4.0	1.713	1.180–2.487	0.005	1.319	0.800–2.174	0.278
Tumor location
Proximal versus remote versus other	1.096	0.876–1.371	0.423
Degree of differentiation
Poorly versus moderately versus well	1.561	0.912–2.672	0.104
Distant metastasis
No versus yes	5.375	3.898–7.410	<0.001	2.939	1.781–4.850	<0.001
Surgery
No versus yes	0.430	0.307–0.626	<0.001	0.973	0.585–1.620	0.917
TNM category (AJCC, 7th)
I + II versus III + IV	6.205	3.035–12.678	<0.001
NLR
≤2.08 versus >2.08	1.946	1.415–2.676	<0.001	1.766	1.136–2.745	0.011
PLR
≤140.63 versus >140.63	1.630	1.199–2.215	0.002	1.373	0.885–2.129	0.157
AGR
≤1.50 versus >1.50	0.649	0.478–0.882	0.006	0.578	0.373–0.897	0.015