White Matter Integrity in Genetic High-Risk Individuals and First-Episode Schizophrenia Patients: Similarities and Disassociations

Table 1

Demographic and clinical data of participants.

	FE-SZ ()	GHR-SZ ()	HC ()
Age (year, mean ± SD)
Sex (F/M)	22/26	23/14	35/32
Handedness (R/L/MIX)	44/1/3	33/1/3	64/0/3	<0.609
Medication (yes/no)	24/24	1/36	N/A
Illness duration (month, mean ± SD)		N/A	N/A
BPRS (mean ± SD)				<0.000
BPRS (subscore_anxiety/depression)				<0.000
BPRS (subscore_Lack of energy)				<0.000
BPRS (subscore_Thought disorder)				<0.000
BPRS (subscore_activition)				<0.000
BPRS (subscore_Hostility/suspicion)				<0.000
Wisconsin_Total Correct				<0.000
Wisconsin_Categories Completed				<0.000
Wisconsin_Total Errors				<0.000
Wisconsin_Perseverative Error				0.069
Wisconsin_Nonperseverative Errors				<0.000

SD: standard deviation.
BPRS: Brief Psychiatric Rating Scale.
FE-SZ: first-episode schizophrenia patients.
GHR-SZ: individuals at genetic high risk for schizophrenia.
HC: healthy controls.
FE-SZ significantly different from HC, .FE-SZ significantly different from GHR-SZ, . GHR-SZ significantly different from HC, .