Sodium Mercaptoethane Sulfonate Reduces Collagenolytic Degradation and Synergistically Enhances Antimicrobial Durability in an Antibiotic-Loaded Biopolymer Film for Prevention of Surgical-Site Infections

Table 1

Trypan Blue Exclusion Assay: L-929 fibroblasts were treated with M/R or M/R + MeSNA extracts for 24 hours. Cell viability was assessed staining harvested cells with Trypan Blue and counted live/dead cells on a hemocytometer were similar among all three groups ( = 0.89).

	Untreated L929 cells; (cells/mL)	L929 Fibroblasts treated with 2% solution of
		M/R Film; (cells/mL)	M/R + MeSNA Film; (cells/mL)
Mean live cells ± standard deviation	1.84 × 10^6  ± 1.75 × 10^5	1.39 × 10^6  ± 1.22 × 10^5	1.55 × 10^6  ± 4.19 × 10^5
Mean dead cells ± standard deviation	6.0 × 10^4  ± 2.12 × 10^4	3.80 × 10^4  ± 3.11 × 10^4	4.80 × 10^4  ± 5.66 × 10^3
% viability	96.89%	97.43%	96.93%