Efficacy and Safety of Halometasone Cream to Treat Chronic Generalized Eczema and the Effects of Halometasone Cream on Serum Cortisol Levels

Table 1

Baseline characteristics.

	Total	Group A	Group B	Group C	value
Age (year)
Range (Min, Max)	22–78	23–78	32–74	22–78
Mean ± SD	54.7 ± 16.1	54.8 ± 14.8	55.0 ± 14.0	54.1 ± 21.0	0.985
Sex
Men, (%)	37 (61.7)	15 (53.6)	15 (88.2)	7 (46.7)
Women, (%)	23 (38.3)	13 (46.4)	2 (11.8)	8 (53.3)
Lesion area (%)	30–60	30–40	41–50	51–60
Disease history (month)
Range (Min, Max)	2–240	3–240	6–120	2–240
Mean ± SD	61.5 ± 57.6	55.8 ± 46.5	53.8 ± 33.7	80.7 ± 89.4	0.332
Lesion status
EASI, Mean ± SD	30.7 ± 8.7	23.9 ± 4.2	34.0 ± 7.5^2	39.8 ± 4.9^1	<0.000
Serum COR, Mean ± SD (µg/dL)	10.9 ± 3.1	11.1 ± 4.3	10.9 ± 2.7	10.7 ± 2.0	0.967

SD: Standard deviation. EASI: eczema area and severity index. COR: Cortisol. One-way ANOVA was performed to compare the three groups. was considered significant different. ¹Significantly higher versus group B () and group A (). ²Significantly higher versus group A ().