Appendectomy as a Risk Factor for Bacteremic Biliary Tract Infection Caused by Antibiotic-Resistant Pathogens

Table 4

Differences between patients with and without antibiotic-resistant bacteria.

	Antibiotic-resistant bacteria
	(+) ( = 34)	(−) ( = 140)	value
Age (mean)	71	69	0.67
Male	19 (56%)	87 (62%)	0.50
Pitt bacteremia score (mean)	1.65	1.11	0.021
Site of biliary tract infection
Cholangitis	29 (85%)	120 (86%)	0.95
Cholecystitis	5 (15%)	20 (14%)	0.95
Cause of biliary tract infection			0.058
No malignancy	18 (53%)	98 (70%)
Malignancy	16 (47%)	42 (30%)
Comorbidity
Chronic kidney disease	10 (29%)	37 (26%)	0.73
Diabetes mellitus	8 (24%)	34 (24%)	0.92
Liver cirrhosis	2 (6%)	19 (14%)	0.21
Medication
Proton pump inhibitor	9 (26%)	34 (24%)	0.80
Corticosteroids	5 (15%)	17 (12%)	0.69
Prior appendectomy	12 (35%)	20 (14%)	0.0046
Antibiotic use within the preceding 3 months	19 (56%)	38 (27%)	0.0014
Indwelling biliary device	15 (44%)	41 (29%)	0.090
Hospitalization within the preceding 30 days	15 (44%)	36 (26%)	0.035
Bilioenteric anastomosis or sphincterotomy	14 (41%)	28 (20%)	0.0096
30-Day mortality	4 (12%)	10 (7%)	0.79