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BioMed Research International
Volume 2017 (2017), Article ID 3505784, 14 pages
https://doi.org/10.1155/2017/3505784
Research Article

Advanced Age as a Predictor of Survival and Weaning in Venoarterial Extracorporeal Oxygenation: A Retrospective Observational Study

1Department of Thoracic and Cardiovascular Surgery, School of Medicine, Konkuk University Chungju Hospital, Konkuk University, Chungju-si, Chungbuk, Republic of Korea
2Department of Internal Medicine and Division of Cardiology, College of Medicine, Hallym University Chuncheon Sacred Heart Hospital, Hallym University, Chuncheon-si, Gangwon-do, Republic of Korea
3Department of Thoracic and Cardiovascular Surgery, College of Medicine, Hallym University Sacred Heart Hospital, Hallym University, Gyeonggi-do, Republic of Korea
4Department of Thoracic and Cardiovascular Surgery, College of Medicine, Hallym University Dongtan Sacred Heart Hospital, Hallym University, Gyeonggi-do, Republic of Korea
5Department of Thoracic and Cardiovascular Surgery, School of Medicine, Konkuk University Seoul Hospital, Konkuk University, Seoul, Republic of Korea
6Department of Surgery, School of Medicine, Konkuk University Chungju Hospital, Konkuk University, Chungju-si, Chungbuk, Republic of Korea
7Department of Thoracic and Cardiovascular Surgery, School of Medicine, Kangwon National University, Chuncheon-si, Gangwon-do, Republic of Korea

Correspondence should be addressed to HeeSung Lee

Received 8 November 2016; Revised 16 January 2017; Accepted 7 March 2017; Published 6 April 2017

Academic Editor: Giovanni Mariscalco

Copyright © 2017 WooSurng Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. In most reports on ECMO treatment, advanced age is classified as a contraindication to VA ECMO. We attempted to investigate whether advanced age would be a main risk factor deciding VA ECMO application and performing VA ECMO support. We determined whether advanced age should be regarded as an absolute or relative contraindication to VA ECMO and could affect weaning and survival rates of VA ECMO patients. Methods. VA ECMO was performed on 135 adult patients with primary cardiogenic shock between January 2010 and December 2014. Successful weaning was defined as weaning from ECMO followed by survival for more than 48 hours. Results. Among the 135 patients, 35 survived and were discharged uneventfully, and the remaining 100 did not survive. There were significant differences in survival between age groups, and older age showed a lower survival rate with statistical significance (P = .01). By multivariate logistic regression analysis, age was not significantly associated with in-hospital mortality (P = .83) and was not significantly associated with VA ECMO weaning (P = .11). Conclusions. Advanced age is an undeniable risk factor for VA ECMO; however, patients of advanced age should not be excluded from the chance of recovery after VA ECMO treatment.