Genotyping the High Altitude Mestizo Ecuadorian Population Affected with Prostate Cancer

Table 1

Different NGS techniques used in prostate cancer studies.

Finding	NGS technology	Year	Reference
Deletion at chromosome 3p14 implicates FOXP1, RYBP, and SHQ1 as potential cooperative tumor suppressors	WES	2010	[21]
TMPRSS2-ERG, CTAGE5-KHDRBS3, and USP9Y-TTTY15 fusions, long noncoding RNAs (long ncRNAs), alternative splicing, and somatic mutations	RNA sequencing; WGS	2011, 2012	[16, 18]
SPOP, FOXA1, and MED12 mutations	WES	2012	[20]
Variant at 8q24 and HOXB13	WGS	2012	[22]
Rearrangements, translocations, and deletions	WGS	2013	[23]
ADP-regulated signaling pathways-inhibitions of Wnt/B catenin signaling pathways	RNA sequencing	2014	[17]
Heterogeneity of AR gene expression, mutations, and splicing variants	Single-cell RNA seq	2015	[19]