Genotyping the High Altitude Mestizo Ecuadorian Population Affected with Prostate Cancer

Table 3

Association between genetic polymorphisms and prostate cancer risk among cases and controls.

Gene	Polymorphism	Genotype	Case versus control
			OR	95% CI	value
SRD5A2	A49T	A/A			Reference
		A/T	0.97	0.56–1.67	1
		T/T	0.40	0.31–0.52	0.000
		A/T + T/T	1.31	0.77–2.22	0.394
	V89L	V/V			Reference
		V/L	0.34	0.19–0.61
		L/L	0.06	0.02–0.20
		V/L + L/L	0.27	0.15–0.48	0.000
MTHFR	C677T	C/C			Reference
		C/T	2.22	1.26–3.92	0.008
		T/T	1.73	0.11–28.73	1
		C/T + T/T	2.21	1.26–3.89	0.008
AR	CAG repeats	≥22 CAGs			Reference
		≤21 CAGs	2.99	1.79–5.01	0.000

OR, odds ratio.