Effect of Gonadotropin Types and Indications on Homologous Intrauterine Insemination Success: A Study from 1251 Cycles and a Review of the Literature

Table 6

Multivariate analysis of IUI success factors.

IUI success factors	Clinical pregnancy			Live birth
	OR	95% CI	value	OR	95% CI	value
COS (hMG versus FSH)	1.11	0.66–1.86	0.70	1.28	0.75–2.17	0.37
Infertility type
Cervical	1.00	—	—	1.00	—	—
Dysovulation	1.14	0.62–2.10	0.69	1.07	0.55–2.07	0.85
PCOS	0.91	0.56–1.48	0.70	0.82	0.48–1.39	0.46
Endometriosis	0.38	0.13–1.10	0.07	0.46	0.16–1.35	0.16
Tubal factor	0.61	0.23–1.64	0.32	0.59	0.20–1.73	0.33
Male factor	0.91	0.56–1.48	0.69	1.00	0.60–1.67	1.00
Unexplained infertility	0.63	0.40–1.00	0.047 (s)	0.68	0.42–1.11	0.13
Female age (≥40 years versus ≤39)	0.17	0.02–1.28	0.09 (s)	0.19	0.03–1.40	0.10
IUI attempt rank (≥4 versus ≤3)	0.51	0.29–0.89	0.02 (s)	0.47	0.25–0.88	0.02 (s)
Sperm quality
Sperm concentration (<15 × 10^6/ml versus >15)	0.81	0.40–1.65	0.56	0.79	0.37–1.66	0.52
Sperm motility (≥40 % versus ≤39)	1.43	0.86–2.39	0.17	1.39	0.80–2.40	0.24
TMS (≥5 × 10^6 versus <5)	1.02	1.00–1.04	0.047 (s)	1.05	0.87–1.28	0.60

Multivariate analysis was performed by logistic models; IUI: intrauterine insemination; COS: controlled ovarian stimulation; PCOS: polycystic ovary syndrome; TMS: total motile sperm count.