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BioMed Research International
Volume 2017, Article ID 3519158, 14 pages
Research Article

XBP1-Mediated BiP/GRP78 Upregulation Copes with Oxidative Stress in Mosquito Cells during Dengue 2 Virus Infection

1Department of Public Health and Parasitology, College of Medicine, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan
2Graduate Institute of Biomedical Sciences, Chang Gung University, Kwei-San, Tao-Yuan, Taiwan
3Environmental Health Department, Banjarnegara Polytechnic, Central Java, Indonesia
4Molecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Kwei-San, Tao-Yuan, Taiwan
5Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children’s Hospital, Chang Gung University College of Medicine, Kwei-San, Tao-Yuan, Taiwan

Correspondence should be addressed to Wei-June Chen; wt.ude.ugc.liam@nehcjw

Received 3 June 2017; Revised 1 August 2017; Accepted 23 August 2017; Published 1 October 2017

Academic Editor: Hong-Lin Su

Copyright © 2017 Tien-Huang Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The supplementary materials include partial sequences of XBP1 derived from C6/36 cells; in which the primer pair used to detect its splicing activity and the fragment (23 nucleotides) expected to be deleted in response to the stress are included. In addition, the nucleotides and deduced amino acids of the BiP/GRP78 open reading frame derived from C6/36 cells were also shown in this part.

  1. Supplementary Material