Psoralen Inhibited Apoptosis of Osteoporotic Osteoblasts by Modulating IRE1-ASK1-JNK Pathway

Figure 2

Psoralen increased the proliferation and inhibited the apoptosis of osteoporotic osteoblasts. (a) Psoralen increased the proliferation of osteoporotic osteoblasts. Osteoporotic osteoblasts treated by DMSO, psoralen, and E2 were incubated for 72 h. The cell viability at different time points was determined by MTT assay. (b) The EDU stain also performed in cells treated as described above with a magnification of 200. (c) Psoralen inhibited the apoptosis of osteoporotic osteoblasts. Osteoporotic osteoblasts were coincubated with DMSO, psoralen, or E2 for 48 h. Then cell apoptosis was determined by Annexin V/PI assay. , compared with control.

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