Thermosensitive Chitosan Hydrogels Containing Polymeric Microspheres for Vaginal Drug Delivery

Figure 5

The in vitro time-dependent TFV release profiles of free TFV, TFV-CTS-SA-GP, MS F, and MS F-CTS-SA-GP at pH 4.5 (a) and pH 7.2 (b); (c) the final cumulative amount of TFV from different dosage forms at pH 4.5 and pH 7.2; different letters indicate significant differences according to Duncan’s multiple range tests ().

(a)

(b)

(c)