Thermosensitive Chitosan Hydrogels Containing Polymeric Microspheres for Vaginal Drug Delivery

Table 3

Kinetic models used for analysis of TFV release rate from MS F, TFV-CTS-SA-GP, and MS F-CTS-SA-GP and their corresponding values.

Formulations	Model name	Model equation
			pH 4.5	pH 7.4
MS F	Zero-order		0.6455	0.6392
	First-order		0.8104	0.7558
	Higuchi		0.8477	0.9489
	Ritger-peppas		0.9301	0.8934
	Weibull		0.9771 ()	0.9905 ()
TFV-CTS-SA-GP	Zero-order		0.7522	0.5288
	First-order		0.9289	0.7009
	Higuchi		0.9218	0.7467
	Ritger-peppas		0.8698	0.8382
	Weibull		0.9961 ()	0.903 ()
MS F-CTS-SA-GP	Zero-order		0.6556	0.6392
	First-order		0.9289	0.7558
	Higuchi		0.8487	0.9489
	Ritger-peppas		0.8698	0.8934
	Weibull		0.9644 ()	0.9905 ()

is the constant of Weibull models.