In Vivo Studies on the Influence of Bacteriophage Preparations on the Autoimmune Inflammatory Process

Figure 5

Influence of “prophylactic” intraperitoneal application (once daily from 3 days before until 5 days after the first dose of collagen) of purified T4 phage preparation and T4 phage lysate on the course of CIA. (a) Purified T4 phage in PBS: 5 × 10⁸ pfu/mouse (control mice received 0.5 ml of PBS i.p.); number of mice in groups: = 8–10. (b) T4 phage lysate: 1 × 10¹⁰ pfu/mouse; number of mice in groups: . in comparison to the control group (Mann–Whitney U test). For clarity reasons only upper or lower error bars representing SE are shown.

(a)

(b)