BioMed Research International / 2017 / Article / Fig 7

Research Article

Recombinant Vaccinia Viruses Coding Transgenes of Apoptosis-Inducing Proteins Enhance Apoptosis But Not Immunogenicity of Infected Tumor Cells

Figure 7

Therapeutic effect of VV-GMCSF-Lact and VV-GMCSF-Apo injected into tumors. (a) Established MDA-MB-231 tumors growing in SCID mice ( in groups) were injected locally with 1 × 107 PFU of viruses followed by monitoring of tumor growth. Tumor growth curves are presented with SE. Arrows indicate the days of virus injections. Viability of treated mice is also represented (b); significant difference compared to the control (saline-treated) group ().

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