Chemopreventive Potential of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside on the Formation of Aberrant Crypt Foci in Azoxymethane-Induced Colorectal Cancer in Rats

Table 1

Effects of THSG on growth characteristics in AOM-induced ACF in rats.

	Food intake (g/d)		Body weight gain (g)
	3 wks	9 wks	3 wks	9 wks
Normal	14.00 ± 0.56	21.22 ± 0.60	121.3 ± 12.65	256.8 ± 12.65
AOM only	14.78 ± 0.15	21.92 ± 0.52	133.2 ± 19.56	270.7 ± 17.36
30 mg THSG	14.45 ± 0.36	21.69 ± 0.26	125.3 ± 20.38	253.3 ± 23.56
150 mg THSG	14.39 ± 0.26	21.33 ± 0.56	127.3 ± 23.12	250.7 ± 24.08
250 mg THSG	14.26 ± 0.28	21.86 ± 0.24	124.7 ± 22.83	255.2 ± 18.72

F344 rats were treated orally with different doses of THSG (30, 150, or 250 mg/kg) for 6 weeks. The average initial body weights among these groups ranged from 243 to 270 g. Data are expressed as means ± SD ().