Intracardiac Hemostasis and Fibrinolysis Parameters in Patients with Atrial Fibrillation
Table 1
Characteristics of atrial fibrillation (AF) patients and controls.
Variables
AF group
non-AF control group
value
Number of patients after exclusions
24
14
Age (years)
56.45 (47.43–59.80)
50.60 (32.80–56.10)
0.061
Male, (%)
15 (62.50)
10 (71.43)
0.728
BMI (kg/m2)
29.43 ± 5.52
26.10 ± 4.75
0.068
Cerebrovascular risk factors, (%)
Arterial hypertension
13 (54.17)
8 (57.14)
1.000
Hypercholesterolemia
19 (79.17)
8 (57.14)
0.266
Current smoking
2 (8.33)
6 (42.86)
0.013
Diabetes mellitus
2 (8.33)
0
—
Previous myocardial infarction, (%)
0
0
—
Previous ischemic stroke, (%)
0
0
—
Heart failure, (%)
1 (4.17)
0
—
Left atrium size (mm)
39.71 ± 4.82
36.55 ± 4.80
0.081
AF period during procedure, (%)
2 (8,33)
—
—
CHADS2 score, (%)
0
10 (41.67)
n.a.
—
1
10 (41.67)
n.a.
—
2
4 (16.67)
n.a.
—
CHA2DS2-VASC score, (%)
0
6 (25.00)
n.a.
—
1
9 (37.50)
n.a.
—
2
5 (20.83)
n.a.
—
3
3 (12.50)
n.a.
—
4
1 (4.17)
n.a.
—
EHRA score, (%)
1
3 (12.50)
n.a.
—
2
1 (4.17)
n.a.
—
3
16 (66.67)
n.a.
—
4
4 (16.67)
n.a.
—
Medication, (%)
Statin
6 (25.00)
2 (14.29)
0.684
ACEI
8 (33.33)
6 (42.86)
0.729
Beta-blocker
17 (70.83)
9 (64.29)
0.728
Laboratory parameters
C-reactive protein (mg/L)
1.50 (0.60–2.75)
1.10 (0.13–2.05)
0.281
Total cholesterol (mmol/L)
5.30 ± 1.16
4.69 ± 1.09
0.122
LDL cholesterol (mmol/L)
3.42 ± 0.98
2.79 ± 0.91
0.061
HDL cholesterol (mmol/L)
1.44 (0.32)
1.46 ± 0.42
0.812
Triglyceride (mmol/L)
1.80 (1.23–2.18)
1.4 (0.75–1.95)
0.208
Zero blood group, (%)
7 (29.17)
2 (14.29)
0.446
Continuous variables are expressed as mean ± SD or median (interquartile range). Categorical variables are indicated as number (percentage), unless otherwise stated. AF: atrial fibrillation; : number; IQR: interquartile range; SD: standard deviation; n.a.: nonapplicable; BMI: body mass index; CHADS2 score: congestive heart failure, hypertension, age ≥ 75 years, diabetes mellitus, stroke/transient ischemic attack; CHA2DS2-VASC score: congestive heart failure, hypertension, age ≥ 75 years, diabetes mellitus, stroke/transient ischemic attack/thromboembolism, vascular disease (prior myocardial infarction, peripheral vascular disease, or aortic atherosclerosis), age (65–74 years), sex category (female); EHRA score: European Heart Rhythm Association score; ACEI: angiotensin converting enzyme inhibitor; LDL cholesterol: low density lipoprotein cholesterol; HDL cholesterol: high density lipoprotein cholesterol.