Outcome of Critically Ill Patients with Testicular Cancer
Table 1
Clinical characteristics of critically ill patients with testicular cancer admitted to the intensive care unit ().
Characteristic
Finding
Age, years, mean ± SD
Primary histology, (%)
Nonseminomatous germ cell tumors
55 (91.7)
Seminoma
5 (8.3)
Metastasis
58 (96.7)
Sites of metastasis, (%)
Pulmonary
6 (10)
Extrapulmonary
17 (28.3)
Mixed
35 (58.3)
Stages, n (%)
IIB/IIC
8 (13.3)
IIIA/IIIB/IIIC
52 (86.7)
IGCCCG, (%)
Good
2 (3.3)
Intermediate
9 (15.0)
Poor
49 (81.7)
Tumor marker, median (IQR)
-Fetoprotein, µg/L
4.17 (2.11–173)
Human chorionic gonadotropin, U/L
2.02 (0–12,189)
Lactate dehydrogenase, U/L
421.5 (194.5–1,304.5)
Characteristics on admission to the ICU
Need for vasopressors, (%)
27 (45)
Need for IMV, (%)
43 (41.7)
Need for hemodialysis, (%)
1 (1.7)
Length of IMV (days), median (IQR)
3 (1–7)
PEEP, median (IQR)
6 (5–9)
In hospital wards time before ICU admission, (%)
49 (81.6)
Length of stay in hospital wards before ICU admission, (days), median (IQR)
2 (1–7)
APACHE score, mean ± SD
MEXSOFA, mean ± SD
Performance status, (%)
0–2
34 (56.7)
3-4
26 (43.3)
Outcome data
Length of stay in ICU, days, median (IQR)
3 (2–6)
Length of hospital stay, days, median (IQR)
8 (5–15)
ICU mortality, (%)
23 (38.3)
Hospital mortality, (%)
27 (45.0)
6-month mortality, (%)
38 (63.3)
SD, standard deviation. IMV, invasive mechanical ventilation. IQR, interquartile range. ICU, intensive care unit. SOFA, sequential organ failure assessment. APACHE, Acute Physiology and Chronic Health Evaluation. SAPS, Simplified Acute Physiology Score. IGCCCG, the International Germ Cell Cancer Collaborative Group.
