Sodium Ferulate Protects against Angiotensin II-Induced Cardiac Hypertrophy in Mice by Regulating the MAPK/ERK and JNK Pathways
Table 2
The comparison of HR, SBP, and DBP among different groups ().
Indexes
Times (d)
Control
PBS
Ang II
Ang II + 10 mg/kg SF
Ang II + 40 mg/kg SF
Ang II + 40 mg/kg SF + 10 mg/kg TBHQ
HR (beats/times)
0
471.9 ± 24.5
477.3 ± 25.4
473.8 ± 25.6
469.9 ± 27.4
471.8 ± 22.6
474.5 ± 26.8
7
472.4 ± 25.8
475.8 ± 26.3
488.2 ± 31.2
479.6 ± 23.5
477.9 ± 24.8
486.5 ± 26.4
14
476.2 ± 29.8
474.6 ± 27.8
507.7 ± 25.5
488.5 ± 27.6
481.2 ± 22.9
508.4 ± 18.6
28
476.9 ± 27.4
481.9 ± 31.6
523.9 ± 27.8
501.9 ± 23.8
479.9 ± 23.5
519.9 ± 19.6
SBP (mmHg)
0
115.4 ± 9.8
116.4 ± 9.5
115.2 ± 10.1
117.4 ± 9.5
115.9 ± 8.6
116.9 ± 11.4
7
116.6 ± 10.5
117.8 ± 11.2
121.8 ± 11.4
118.9 ± 10.5
117.4 ± 9.7
122.0 ± 12.2
14
118.2 ± 11.6
117.5 ± 10.5
127.5 ± 10.3
122.4 ± 11.3
119.9 ± 10.8
126.8 ± 9.8
28
117.8 ± 11.2
119.7 ± 10.6
139.5 ± 10.6
127.8 ± 9.9
121.9 ± 11.6
DBP (mmHg)
0
82.8 ± 8.1
81.6 ± 7.8
83.9 ± 8.0
84.1 ± 8.5
84.4 ± 8.2
85.2 ± 9.4
7
84.5 ± 8.2
82.5 ± 7.9
85.5 ± 9.1
84.9 ± 8.4
85.1 ± 8.9
86.5 ± 10.1
14
83.1 ± 8.5
84.0 ± 8.4
86.9 ± 9.6
85.2 ± 9.2
85.5 ± 9.2
85.9 ± 9.5
28
84.1 ± 7.9
83.3 ± 8.1
88.2 ± 11.4
87.1 ± 10.2
86.2 ± 9.8
84.9 ± 9.2
Note. Compared with Sham group, the difference had statistical significance, . Compared with PBS group, the difference had statistical significance, . Compared with Ang II group, the difference had statistical significance, . Compared with that at 0 d, the difference had statistical significance, .
