Possible Effect of Concomitant Prokinetics and Herbal Medicines against Nausea in Patients Taking Lubiprostone

Table 2

Relationship between nausea/vomiting after administration of lubiprostone and clinical factors based on univariate analysis.

Clinical factor	Odds ratio	95% confidence interval	value
Age	0.956	0.924–0.988	0.007
Sex	0.310	0.094–1.021	0.054
Mental disorder	0.759	0.258–6.414	0.759
Laxatives	0.898	0.372–3.082	0.898
Prokinetics/herbal medicines	0.037	0.067–0.920	0.037
Probiotics	0.790	0.088–6.333	0.790
PPI/H2RA	0.364	0.078–1.696	0.198

PPI: proton pump inhibitor and H2RA: histamine 2 receptor antagonist.