Research Article
First-Line Helicobacter pylori Eradication in Patients with Chronic Kidney Diseases in Taiwan
Table 1
Demographic data and endoscopic appearances of the two patient groups.
| | | CKD
()
(%) | Control
non-CKD ()
(%) | value |
| | Age (year) (mean ± SD) | | 58.2 ± 11.3 | <0.001 | | Sex (male/female) | 53/77 | 303/325 | 0.120 | | Smoking, (%) | 14 (10.8) | 94 (15.0) | 0.213 | | Alcohol consumption, (%) | 14 (10.8) | 101 (16.1) | 0.124 | | Previous history of peptic ulcer, (%) | 39 (30.0) | 106 (16.9) | 0.001 | | Endoscopic findings, (%) | | | | | Gastritis | 35 (26.9) | 214 (34.1) | | | Gastric ulcer | 60 (46.2) | 190 (30.3) | 0.002 | | Duodenal ulcer | 22 (16.9) | 169 (26.9) | | | Gastric and duodenal ulcer | 13 (10.0) | 55 (8.8) | | | Laboratory data (mean ± SD) | | | | | AST (U/L) | 29.1 ± 13.8 | 28.8 ± 21.4 | 0.921 | | ALT (U/L) | 25.2 ± 15.4 | 31.4 ± 29.4 | 0.051 | | Total bilirubin (mg/dl) | 0.7 ± 0.5 | 1.9 ± 1.3 | 0.564 | | Albumin (g/dl) | 4.2 ± 0.3 | 4.4 ± 0.6 | 0.089 | | Total protein (g/dl) | 7.0 ± 0.4 | 7.7 ± 6.8 | 0.716 | | BUN (mg/dl) | 33.2 ± 22.2 | 14.2 ± 20.0 | <0.001 | | Na (mEq/L) | 137.0 ± 18.9 | 139.3 ± 11.2 | 0.231 | | K (mEq/L) | 5.9 ± 2.7 | 4.2 ± 2.9 | 0.024 | | Ca (mEq/L) | 9.3 ± 0.8 | 11.0 ± 13.0 | 0.480 | | Cl (mEq/L) | 97.5 ± 24.4 | 104.5 ± 10.4 | 0.029 | | GFR (ml/min/1.73 m2) | 39.0 ± 16.6 | 90.1 ± 19.3 | <0.001 | | Hemoglobin (g/dL) | 11.4 ± 2.2 | 13.7 ± 3.1 | <0.001 | | Cholesterol (mg/dl) | 168.1 ± 29.5 | 189.2 ± 38.8 | 0.001 | | Triglyceride (mg/dl) | 152.6 ± 80.0 | 126.4 ± 79.9 | 0.055 |
|
|
CKD: chronic kidney disease, AST: aspartate aminotransferase; ALT: alanine aminotransferase, BUN: blood urea nitrogen, GFR: glomerular filtration rate, Na: sodium, K: potassium, Cl: chloride, and Ca: calcium.
|
