BioMed Research International / 2017 / Article / Tab 3

Research Article

Application of the Subtractive Genomics and Molecular Docking Analysis for the Identification of Novel Putative Drug Targets against Salmonella enterica subsp. enterica serovar Poona

Table 3

Druggable targets, available drugs, and broad-spectrum property analysis of the shortlisted essential proteins from Salmonella enterica subsp. enterica serovar Poona.

Target number KEEG orthology (KO) Protein name Broad-spectrum property Available drug in DrugBank DrugBank IDs

()K01775Alanine racemase25CycloserineDB00260

()K00790 UDP-N-Acetyl glucosamine 1-carboxyvinyltransferase 19FosfomycinDB00828

()K05515Penicillin-binding protein 28Ceftazidime
Ertapenem
DB00438
DB00303

()K12340Outer membrane channel protein tolC28ColistinDB00803

()K09476Outer membrane pore protein F26Polymyxin B SulfateDB00781

()K03531Cell division protein FtsZ29Guanosine 5′-diphosphateDB04315

()K016272-Dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase)82-Phosphoglyceric acidDB01709

()K02563UDP-N-Acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase29Uridine diphosphate-N-acetylgalactosamineDB02196

()K07637Two-component system, OmpR family, sensor histidine kinase PhoQ197RadicicolDB03758

()K07638Two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ32Phosphoaminophosphonic acid-adenylate esterDB04395

()K18138Multidrug efflux pump arcB279Rhodamine 6gDB03825

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