Home Remodeling and Food Allergy Interact Synergistically to Increase the Risk of Atopic Dermatitis
Table 3
Risk factors for lifetime diagnosis of AD.
Risk factors
(%)
435/4,111 (10.6%)
(95% CI)
P value
Demographic factors
Age (older)
0.96 (0.85–1.07)
0.431
Sex (girl)
1.69 (1.10–2.58)
0.016
BMI
1.03 (0.95–1.11)
0.514
Educational status of the mother (≥university graduate)
1.61 (0.99–2.62)
0.053
Economic status (higher monthly income)
1.12 (0.84–1.48)
0.436
Personal factors
Lifetime diagnosis of FA
3.95 (2.00–7.83)
<0.001
Lifetime diagnosis of asthma
3.38 (1.72–6.67)
<0.001
Lifetime diagnosis of allergic rhinitis
2.37 (1.57–3.60)
<0.001
Breast milk feeding
1.55 (0.94–2.58)
0.089
Premature birth
1.86 (0.89–3.91)
0.101
Delivery (Cesarean section)
0.96 (0.63–1.46)
0.858
Genetic factors
Parental history of allergic diseases
(2.04–5.10)
<0.001
Parental history of AD
(1.47–4.83)
0.001
Parental history of asthma
2.16 (0.90–5.21)
0.087
Parental history of allergic rhinitis
2.46 (1.60–3.79)
<0.001
Parental history of FA
2.35 (1.31–4.24)
0.004
Environmental factors
Dog ownership
0.61 (0.18–2.10)
0.432
Cat ownership
1.48 (0.23–9.51)
0.681
Day care attendance before 1 year old
0.66 (0.18–2.39)
0.523
Older siblings
0.76 (0.51–1.13)
0.174
Home remodeling, ever
1.37 (0.89–2.12)
0.151
Home remodeling in infancy
0.86 (0.16–4.78)
0.864
Home remodeling in the past 12 months
3.40 (1.43–8.09)
0.006
Moving to new home in infancy
0.98 (0.62–1.56)
0.944
Biomarkers
Eosinophil > 4%
(1.54–3.62)
<0.001
Eosinophil 4th quartile (>5.0%)
(1.57–3.94)
<0.001
The data were calculated by logistic regression multivariate analysis. aOR: adjusted odds ratio; CI: confidence interval; BMI: body mass index; FA: food allergy; AD: atopic dermatitis. was adjusted by age, sex, BMI, parental history of AD, familial income, and eosinophil. was adjusted by age, sex, BMI, familial income, and eosinophil. was adjusted by age, sex, BMI, parental history of AD, and familial income. Significant aOR and values are in bold.
