Hypothyroidism Reduces the Size of Ovarian Follicles and Promotes Hypertrophy of Periovarian Fat with Infiltration of Macrophages in Adult Rabbits

Figure 1

Follicle morphometry in control and hypothyroid rabbits. Atretic follicles: (a) cystic (Cyst), (b) invasive (Inv), (c) obliterative (Obli), and (d) residual (Res). Bars: (a) 500 μm, (b-c) 200 μm, and (d) 20 μm. Granulose cells, gc; theca cells, tc; and connective tissue, ct. (e) Percentage of ovarian functional and atretic follicles of control (open bars; ) and hypothyroid (solid bars; ) females rabbits. (f) Functional follicles were classified as primordial (P), primary (1), secondary (2), tertiary (3), and Graafian (G). (g) For atretic follicles, the different type of atresia mentioned above was analyzed. Data are mean ± SEM.

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